The Messenger of Allah (ﷺ), used to recite this du'a when he was on a journey:

اَللَّهُمَّ إِنِّي أَسْأَلُكَ فِي سَفَرِيْ هَذَا مِنَ الْبِرِّ وَالتَّقْوَى وَمِنَ الْعَمَلِ مَا تَرْضَى، اَللَّهُمَّ هَوِّنْ عَلَيْنَا الْمَسِيرَ وَاطْوِ عَنَّا بُعْدَ الْأَرْضِ اَللَّهُمَّ أَنْتَ الصَّاحِبُ فِي السَّفَرِ وَالْخَلِيفَةُ فِي الْأَهْلِ اَللَّهُمَّ اصْحَبْنَا فِي سَفَرِنَا وَاخْلُفْنَا فِي أَهْلِنَا

Allaahumma inni as’aluka fi safari hadha minal-birri wat-taqwa, wa minal-`amali maa tarda. Allaahumma hawwin `alainal-masira, watwi `anna bu`dal-ard. Allaahumma antas-saahibu fis safari wal-khalifatu fil-ahli. Allaahumma ashaabna fi safarina wakhlufna fi ahlina

O Allah, I ask You in this journey of mine from the righteousness and piety and actions that which you are pleased with. O Allah, ease for us the path, and make near for us the distance of the land. O Allah, You are the companion in the journey, and the caretaker for the family. O Allah, accompany us in our journey, and take care of our families

Reference: Sahih (Albani). Tirmidhi: 3447